buy deca durabolin

Mekciprim refers to heteroaromatic antioxidants. It has a wide spectrum of pharmacological activity: it increases the body’s resistance to stress, exhibit anxiolytic effect is not accompanied by drowsiness and muscle relaxant effect; It has nootropic properties, prevents and reduces disorders of learning and memory that occur with aging and exposure razlichnyk pathogenic factors; It buy deca durabolin has anticonvulsant effect; shows antioxidant properties and antihypoxic; It improves concentration and performance; It weakens the toxic effect of alcohol. The drug improves the metabolism of the brain tissue and the blood circulation, improves microcirculation and blood rheology, reduces platelet aggregation. It stabilizes the membrane structure of the blood cells (red blood cells, and platelets). Has hypolipidemic effect, reduces total cholesterol and low density lipoprotein. The mechanism of action meksiprima due to its antioxidant and membrane action. It inhibits lipid peroxidation, increases the activity of superoksidoksidazy, increases the ratio of lipid-protein, reduces the viscosity of the membrane increases its fluidity. Modulates the activity of membrane-bound enzymes (kaltsiyvezavisimoy phosphodiesterase, adenylate cyclase, acetylcholinesterase) receptor complexes (benzodiazepine, GABA, acetylcholine), which enhances their ability to bind to ligands, it helps to preserve the structural and functional organization of biological membranes, transport of neurotransmitters and improve synaptic transmission. Meksiprim content increases brain dopamine. It is a compensatory increase in the activation of aerobic glycolysis and decreased inhibition of oxidative processes in the Krebs cycle under hypoxic conditions where to buy deca durabolin with increasing the content of ATP and creatine phosphate, activation energosinteziruyuschih functions of mitochondria, stabilizing cell membranes.

Pharmacokinetics. Meksiprim rapidly absorbed from the gastrointestinal tract with poluabsorbtsii period of 0.08-0.1 hours. Time to reach maximum plasma concentration of 0,46-0,5 hours. Meksiprima size maximum plasma concentration in the range from 50 to 100 ng / ml. The half-life meksiprima and mean residence time of the drug in the body are respectively 4,7-5, hour and 4.9-5.2 hours. Meksiprim in humans is metabolized rapidly to form its glyukuronokonyugirovannogo product. On average, 12 hours for urine excreted buy deca durabolin unchanged drug 0.3% and 50% of the administered dose glyukuronokonyugata. The most intensive mexidol and glyukuronokonyugat excreted during the first 4 hours after ingestion. Indicators excretion in the urine meksiprima and its conjugated metabolites have considerable individual variability.

Indications

anxiety disorders in neurotic and neurosis-like states;

  • vegetative-vascular dystonia;
  • mild cognitive disorders of various origins (when psychoorganic syndrome and asthenic disorders caused by acute and chronic disorders of cerebral circulation, brain injuries, intoxication and neuroinfections, senile and atrophic processes);
  • memory disorders and intellectual impairment in the elderly;
  • exposure to extreme (stress) factors;
  • alcohol withdrawal syndrome with prevalence of neurosis and vegetative-vascular disorders.Contraindications: Liver and / or kidney failure, increased individual sensitivity to the drug, infancy, pregnancy, breastfeeding.Dosing and Administration Meksiprim appointed interior. Applied therapeutic dose and duration of treatment is determined by the sensitivity of patients to the drug. Begin treatment with a dose of 0.25-0.5 g; the average daily dose is 0.25-0.5 grams, the maximum daily – 0.8 g daily dose of the drug is distributed into 2-3 doses throughout the day. For the treatment of patients with anxiety disorders, vegetative-vascular dysfunction and cognitive impairment are used meksprim for 2-6 weeks. When coping with alcohol withdrawal syndrome meksiprim used within 5-7 days. Course therapy meksiprimom end gradually decreasing for 2-3 days dose.

    Side effects: Rarely – nausea, dryness of the mouth, drowsiness, allergic reactions.

    Overdose The effects of overdose have buy deca durabolin not been established.

    Interaction with other drugs Meksiprim compatible with psychotropic drugs; It enhances the action of benzodiazepine anxiolytics, antiparkinsonian and carbamazepine. It reduces the toxic effects of ethanol.

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